Identification of DNA methylation-regulated genes as potential biomarkers for coronary heart disease via machine learning in the Framingham Heart Study.

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第一作者： Xiaokang,Zhang

第一单位： Center for Gene Diagnosis and Department of Clinical Laboratory Medicine, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, 430071, China.

作者： Xiaokang,Zhang ^[1] ; Chen,Wang ^[1] ; Dingdong,He ^[1] ; Yating,Cheng ^[2] ; Li,Yu ^[1] ; Daoxi,Qi ^[1] ; Boyu,Li ^[1] ; Fang,Zheng ^[1]

作者单位： Center for Gene Diagnosis and Department of Clinical Laboratory Medicine, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, 430071, China. ^[1] Department of Clinical Laboratory Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, China. ^[2] Center for Gene Diagnosis and Department of Clinical Laboratory Medicine, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, 430071, China. zhengfang@whu.edu.cn. ^[3]

关键词 Coronary heart disease DNA methylation Machine learning Monocyte Transcriptome

主题词碱性亮氨酸拉链转录因子类(Basic-Leucine Zipper Transcription Factors);冠心病(Coronary Disease);DNA甲基化(DNA Methylation);人类(Humans);纵向研究(Longitudinal Studies)

DOI 10.1186/s13148-022-01343-2

PMID 36180886

发布时间 2022-10-04

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准确一般字义偏差语意偏离译文作用小提交