首页> Molecular therapy : the journal of the American Society of Gene Therapy> Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model.

Accelerated DNA vaccine regimen provides protection against Crimean-Congo hemorrhagic fever virus challenge in a macaque model.

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第一作者： David W,Hawman

第一单位： Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.

作者： David W,Hawman ^[1] ; Kimberly,Meade-White ^[1] ; Shanna,Leventhal ^[1] ; Sofia,Appelberg ^[2] ; Gustaf,Ahlén ^[3] ; Negin,Nikouyan ^[3] ; Chad,Clancy ^[4] ; Brian,Smith ^[4] ; Patrick,Hanley ^[4] ; Jamie,Lovaglio ^[4] ; Ali,Mirazimi ^[5] ; Matti,Sällberg ^[6] ; Heinz,Feldmann ^[7]

作者单位： Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA. ^[1] Public Health Agency of Sweden, 171 82, Solna, Sweden. ^[2] Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, 141 86 Stockholm, Sweden. ^[3] Rocky Mountain Veterinary Branch, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA. ^[4] Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, 141 86 Stockholm, Sweden; Public Health Agency of Sweden, 171 82, Solna, Sweden; National Veterinary Institute, 751 89 Uppsala, Sweden. Electronic address: ali.mirazimi@ki.se. ^[5] Division of Clinical Microbiology, Department of Laboratory Medicine, Karolinska Institutet, 141 86 Stockholm, Sweden. Electronic address: matti.sallberg@ki.se. ^[6] Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, MT 59840, USA. Electronic address: feldmannh@niaid.nih.gov. ^[7]

关键词 CCHF Crimean-Congo hemorrhagic fever DNA vaccine correlates of protection macaque model vaccine

医学主题词动物(Animals);出血热病毒, 克里米亚-刚果(Hemorrhagic Fever Virus, Crimean-Congo);出血热, 克里米亚(Hemorrhagic Fever, Crimean);疫苗, DNA(Vaccines, DNA);猕猴属(Macaca);接种(Vaccination)

DOI 10.1016/j.ymthe.2022.09.016

PMID 36184852

发布时间 2024-02-02

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