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Disabling partners in crime: Gold nanoparticles disrupt multicellular communications within the tumor microenvironment to inhibit ovarian tumor aggressiveness.

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第一作者： Yushan,Zhang

第一单位： Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.;Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.

作者： Yushan,Zhang ^[1] ; Chandra Kumar,Elechalawar ^[1] ; Wen,Yang ^[2] ; Alex N,Frickenstein ^[2] ; Sima,Asfa ^[1] ; Kar-Ming,Fung ^[1] ; Brennah N,Murphy ^[1] ; Shailendra K,Dwivedi ^[3] ; Geeta,Rao ^[1] ; Anindya,Dey ^[3] ; Stefan,Wilhelm ^[4] ; Resham,Bhattacharya ^[3] ; Priyabrata,Mukherjee ^[1]

作者单位： Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.;Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. ^[1] Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA. ^[2] Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.;Department of Obstetrics and Gynecology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA. ^[3] Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA.;Stephenson School of Biomedical Engineering, University of Oklahoma, Norman, Oklahoma, 73019, USA.;Institute for Biomedical Engineering, Science, and Technology (IBEST), Norman, Oklahoma, 73019, USA. ^[4]

关键词 Cancer-associated fibroblast (CAF)Epithelial ovarian cancer (EOC)Epithelial-mesenchymal transition (EMT)Gold nanoparticle (GNP, AuNP)Tumor microenvironment (TME)

DOI 10.1016/j.mattod.2022.01.025

PMID 36188120

发布时间 2024-06-07

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