Brain Alterations in Aged OVT73 Sheep Model of Huntington's Disease: An MRI Based Approach.

导出 OA

翻译打印收藏纠错

作者： Toloo,Taghian ^[1] ; Jillian,Gallagher ^[2] ; Erin,Batcho ^[1] ; Caitlin,Pullan ^[3] ; Tim,Kuchel ^[4] ; Thomas,Denney ^[4] ; Raj,Perumal ^[3] ; Shamika,Moore ^[4] ; Robb,Muirhead ^[4] ; Paul,Herde ^[4] ; Daniel,Johns ^[4] ; Chris,Christou ^[4] ; Amanda,Taylor ^[4] ; Thomas,Passler ^[5] ; Sanjana,Pulaparthi ^[3] ; Erin,Hall ^[1] ; Sundeep,Chandra ^[1] ; Charles A,O'Neill ^[6] ; Heather,Gray-Edwards ^[7]

作者单位： Horae Gene Therapy Center, University of Massachusetts Medical School, Worcester, MA, USA. ^[1] Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA. ^[2] Department of Electrical and Computer Engineering, Auburn University, Auburn, AL, USA. ^[3] South Australian Health and Medical Research Institute, Gillies Plains, SA, Australia. ^[4] Department of Clinical Sciences, Auburn University, Auburn, AL, USA. ^[5] Sana Biotechnology, South San Francisco, CA, USA. ^[6] Bio Marin Pharmaceutical Inc., San Rafael, CA, USA. ^[7]

关键词 Huntington’s disease clinical translation diffusion tensor imaging large animal model magnetic resonance spectroscopy transgenic OVT73 sheep model of Huntington’s disease