Meta-GWAS identifies the heritability of acute radiation-induced toxicities in head and neck cancer.
作者:
Elnaz,Naderi [1]
;
Line M H,Schack [2]
;
Ceilidh,Welsh [3]
;
Adelene Y L,Sim [4]
;
Miguel E,Aguado-Barrera [5]
;
Tom,Dudding [6]
;
Holly,Summersgil [7]
;
Laura,Martínez-Calvo [5]
;
Enya H W,Ong [8]
;
Yasmin,Odding [9]
;
Ana,Varela-Pazos [10]
;
Roel J H M,Steenbakkers [11]
;
Anne P G,Crijns [11]
;
Rajesh,Jena [12]
;
Miranda,Pring [13]
;
Joe,Dennis [14]
;
Ramón,Lobato-Busto [15]
;
Jan,Alsner [16]
;
Andy,Ness [13]
;
Christopher,Nutting [17]
;
David J,Thomson [18]
;
Antonio,Gómez-Caamaño [19]
;
Jesper G,Eriksen [20]
;
Steve J,Thomas [13]
;
Amy M,Bates [12]
;
Jens,Overgaard [16]
;
Luis M,Cascallar-Caneda [10]
;
Fréderic,Duprez [21]
;
Gillian C,Barnett [12]
;
Leila,Dorling [14]
;
Melvin L K,Chua [22]
;
Ana,Vega [5]
;
Catharine M L,West [23]
;
Johannes A,Langendijk [11]
;
Christian,Nicolaj Andreassen [24]
;
Behrooz Z,Alizadeh [25]
;
On the behalf of the Radiogenomics Consortium
作者单位:
Department of Radiation Oncology, University Medical Center Groningen, Groningen, the Netherlands; Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands. Electronic address: b.z.alizadeh@umcg.nl.
[1]
Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark; Department of Oncology, Regional Hospital West Jutland, Gødstrup, Denmark.
[2]
Department of Oncology, University of Cambridge, Cambridge, UK.
[3]
Division of Radiation Oncology, Dept of Head and Neck and Thoracic Cancers, Duke-NUS Medical School, Singapore, Singapore; Division of Medical Sciences, National Cancer Centre, Singapore.
[4]
Fundación Pública Galega Medicina Xenómica (FPGMX), Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
[5]
Bristol Dental School, University of Bristol, Bristol, UK; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
[6]
Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, UK.
[7]
Division of Medical Sciences, National Cancer Centre, Singapore.
[8]
University Hospitals Bristol and Weston, Bristol, UK.
[9]
Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
[10]
Department of Radiation Oncology, University Medical Center Groningen, Groningen, the Netherlands.
[11]
Department of Oncology, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
[12]
Bristol Dental School, University of Bristol, Bristol, UK.
[13]
Centre for Cancer Genetic Epidemiology, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.
[14]
Department of Medical Physics, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
[15]
Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark.
[16]
Head and Neck Unit, The Royal Marsden Hospital, London, UK.
[17]
Christie Hospital NHS Foundation Trust, Manchester, UK; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
[18]
Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain; Department of Radiation Oncology, Complexo Hospitalario Universitario de Santiago, SERGAS, Santiago de Compostela, Spain.
[19]
Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark; Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.
[20]
Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
[21]
Division of Radiation Oncology, Dept of Head and Neck and Thoracic Cancers, Duke-NUS Medical School, Singapore, Singapore; Division of Radiation Oncology, National Cancer Centre, Singapore.
[22]
Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie NHS Foundation Trust Hospital, Manchester, UK.
[23]
Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark; Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom.
[24]
Department of Epidemiology, University Medical Center Groningen, Groningen, the Netherlands. Electronic address: b.z.alizadeh@umcg.nl.
[25]
主题词
人类(Humans);吞咽障碍(Deglutition Disorders);全基因组关联研究(Genome-Wide Association Study);黏膜炎(Mucositis);头颈部肿瘤(Head and Neck Neoplasms);辐射损伤(Radiation Injuries);疾病遗传易感性(Genetic Predisposition to Disease);多态性, 单核苷酸(Polymorphism, Single Nucleotide)
DOI
10.1016/j.radonc.2022.09.016
PMID
36191651
发布时间
2024-02-10
- 浏览1
Radiotherapy and oncology
138-148页
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