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High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike.

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第一作者: Timothy J C,Tan
第一单位: Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
作者单位: Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. [1] Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. [2] Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. [3] Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. [4] Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.;IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.;Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA. [5] Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.;IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.;Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.;The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. [6] Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. [7] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. [8] Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.;Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.;Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.;Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. [9]
DOI 10.1101/2022.09.24.509341
PMID 36203547
发布时间 2024-12-07
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