Intestinal mucin is a chaperone of multivalent copper.

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第一作者： Nava,Reznik

第一单位： Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.

作者： Nava,Reznik ^[1] ; Annastassia D,Gallo ^[2] ; Katherine W,Rush ^[3] ; Gabriel,Javitt ^[1] ; Yael,Fridmann-Sirkis ^[4] ; Tal,Ilani ^[1] ; Noa A,Nairner ^[1] ; Simon,Fishilevich ^[5] ; David,Gokhman ^[5] ; Kelly N,Chacón ^[6] ; Katherine J,Franz ^[2] ; Deborah,Fass ^[7]

作者单位： Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. ^[1] Department of Chemistry, Duke University, Durham, North Carolina 27708, United States. ^[2] Department of Chemistry, Reed College, Portland, Oregon 97202, United States; Oregon Health & Science University, Portland, Oregon 97239, United States. ^[3] Life Sciences Core Facilities, Weizmann Institute of Science, Rehovot 7610001, Israel. ^[4] Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel. ^[5] Department of Chemistry, Reed College, Portland, Oregon 97202, United States. ^[6] Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: deborah.fass@weizmann.ac.il. ^[7]

关键词 ascorbic acid copper dietary mineral essential trace element histidine intestine methionin mucin mucus reactive oxygen species

主题词黏蛋白类(Mucins);黏蛋白2(Mucin-2);铜(Copper);肠(Intestines);黏液(Mucus);肠黏膜(Intestinal Mucosa)

DOI 10.1016/j.cell.2022.09.021

PMID 36206754

发布时间 2023-01-25

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