Leveraging the Exploratory and Predictive Capabilities of Design of Experiments in Development of Intraarticular Injection of Imatinib Mesylate Containing Lipospheres.

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作者： Amruta,Gorajiya ^[1] ; Anita,Lalwani ^[2]

作者单位： R and D - Injectables, Amneal Pharmaceuticals, Ahmedabad, India. ^[1] K. B. Institute of Pharmaceutical Education and Research, Gh 6 Road, Sector 23, Gandhinagar, 382023, Gujarat, India. anita.lalwani@kbiper.ac.in. ^[2]

关键词 Monte Carlo simulation exploratory factor analysis imatinib mesylate intraarticular lipospheres principal component analysis

主题词乳状剂(Emulsions);甘油(Glycerol);注射, 关节内(Injections, Intra-Articular);二氯甲烷(Methylene Chloride);氮(Nitrogen);粒子大小(Particle Size);磷脂酰胆碱类(Phosphatidylcholines);钠(Sodium);甘油三酯类(Triglycerides)

DOI 10.1208/s12249-022-02431-5

PMID 36207604

发布时间 2022-10-25

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AAPS PharmSciTech

2022年23卷7期

275页

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Leveraging the Exploratory and Predictive Capabilities of Design of Experiments in Development of Intraarticular Injection of Imatinib Mesylate Containing Lipospheres.

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Leveraging the Exploratory and Predictive Capabilities of Design of Experiments in Development of Intraarticular Injection of Imatinib Mesylate Containing Lipospheres.

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