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Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis.

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第一作者： Tália,Feijão

第一单位： Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139 Faro, Portugal.;Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, 4200-135 Portugal.;Department of Medical Sciences and Institute for Biomedicine, Universidade de Aveiro, 3810-193 Aveiro, Portugal.

作者： Tália,Feijão ^[1] ; Bruno,Marques ^[2] ; Rui D,Silva ^[3] ; Célia,Carvalho ^[4] ; Daniel,Sobral ^[5] ; Ricardo,Matos ^[2] ; Tian,Tan ^[6] ; António,Pereira ^[7] ; Eurico,Morais-de-Sá ^[7] ; Hélder,Maiato ^[7] ; Steven Z,DeLuca ^[6] ; Rui Gonçalo,Martinho ^[8]

作者单位： Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139 Faro, Portugal.;Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, 4200-135 Portugal.;Department of Medical Sciences and Institute for Biomedicine, Universidade de Aveiro, 3810-193 Aveiro, Portugal. ^[1] Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139 Faro, Portugal. ^[2] Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139 Faro, Portugal.;Faculty of Medicine and Biomedical Sciences, Universidade do Algarve, 8005-139 Faro, Portugal. ^[3] Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal. ^[4] Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University Lisbon, 2819-516 Caparica, Portugal.;Applied Molecular Biosciences Unit (UCIBIO), Department of Life Sciences, School of Science and Technology, NOVA University Lisbon, Caparica, 2819-516 Portugal. ^[5] Department of Biology, Brandeis University, Waltham, MA 02453. ^[6] Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, 4200-135 Portugal. ^[7] Algarve Biomedical Center Research Institute, Universidade do Algarve, 8005-139 Faro, Portugal.;Department of Medical Sciences and Institute for Biomedicine, Universidade de Aveiro, 3810-193 Aveiro, Portugal.;Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisboa, Portugal. ^[8]

关键词 Polycomb group proteins meiosis polycomplexes synaptonemal complex transcription

医学主题词染色体蛋白质类, 非组蛋白(Chromosomal Proteins, Non-Histone);染色体配对(Chromosome Pairing);女(雌)性(Female);人类(Humans);减数分裂(Meiosis);减数分裂前期Ⅰ(Meiotic Prophase I);联会复合体(Synaptonemal Complex)

DOI 10.1073/pnas.2204701119

PMID 36215502

发布时间 2024-05-14

基金项目

R01 GM084947/GM/NIGMS NIH HHS/United States

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