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Rose Bengal inhibits β-amyloid oligomers-induced tau hyperphosphorylation via acting on Akt and CDK5 kinases.

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第一作者： Chen-Ye,Mou

第一单位： The Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315211, China.;Translational Medicine Center of Pain, Emotion and Cognition, Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, China.

作者： Chen-Ye,Mou ^[1] ; Yan-Fei,Xie ^[2] ; Jia-Xin,Wei ^[3] ; Qi-Yao,Wang ^[2] ; Jing-Yang,Le ^[2] ; Yong-Jie,Bao ^[2] ; Pan-Pan,Zhang ^[2] ; Yue-Chun,Mao ^[2] ; Xing-Han,Huang ^[2] ; Han-Bo,Pan ^[2] ; C Benjamin,Naman ^[4] ; Lin,Liu ^[5] ; Hong-Ze,Liang ^[6] ; Xiang,Wu ^[5] ; Jia,Xu ^[1] ; Wei,Cui ^[7]

作者单位： The Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315211, China.;Translational Medicine Center of Pain, Emotion and Cognition, Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, China. ^[1] Translational Medicine Center of Pain, Emotion and Cognition, Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, China. ^[2] The Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315211, China.;Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, School of Food and Pharmaceutical Sciences, Ningbo University, Ningbo, 315211, China. ^[3] Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Research Center, School of Food and Pharmaceutical Sciences, Ningbo University, Ningbo, 315211, China. ^[4] The Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315211, China. ^[5] School of Materials Science and Chemical Engineering, Ningbo University, Ningbo, 315211, China. ^[6] The Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315211, China. cuiwei@nbu.edu.cn.;Translational Medicine Center of Pain, Emotion and Cognition, Ningbo Key Laboratory of Behavioral Neuroscience, Zhejiang Provincial Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, 315211, China. cuiwei@nbu.edu.cn. ^[7]

关键词 Alzheimer’s disease CDK5 GSK3β Rose Bengal Tau