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Spatial Transcriptomic Analysis Reveals Associations between Genes and Cellular Topology in Breast and Prostate Cancers.

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第一作者： Lujain,Alsaleh

第一单位： Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN 46202, USA.

作者： Lujain,Alsaleh ^[1] ; Chen,Li ^[2] ; Justin L,Couetil ^[3] ; Ze,Ye ^[2] ; Kun,Huang ^[4] ; Jie,Zhang ^[5] ; Chao,Chen ^[2] ; Travis S,Johnson ^[6]

作者单位： Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN 46202, USA. ^[1] Department of Biomedical Informatics, Stony Brook University, Stony Brook, NY 11794, USA. ^[2] Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN 46202, USA. ^[3] Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN 46202, USA.;Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN 46202, USA.;Regenstrief Institute, Indiana University, Indianapolis, IN 46202, USA.;Melvin and Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN 46202, USA. ^[4] Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN 46202, USA.;Melvin and Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN 46202, USA. ^[5] Department of Biostatistics and Health Data Science, Indiana University, Indianapolis, IN 46202, USA.;Melvin and Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN 46202, USA.;Indiana Biosciences Research Institute, Indianapolis, IN 46202, USA. ^[6]

关键词 breast cancer gene expression histopathological images image analysis integrative analysis prostate cancer spatial transcriptomics topological data analysis

DOI 10.3390/cancers14194856

PMID 36230778

发布时间 2023-10-20

基金项目

R21 CA264339/CA/NCI NIH HHS/United States R21264339/CA/NCI NIH HHS/United States T32 GM077229/GM/NIGMS NIH HHS/United States R01GM148970/GM/NIGMS NIH HHS/United States R01CA253368/CA/NCI NIH HHS/United States R01 GM148970/GM/NIGMS NIH HHS/United States

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