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Mechanistic Understanding of the Olfactory Neuroepithelium Involvement Leading to Short-Term Anosmia in COVID-19 Using the Adverse Outcome Pathway Framework.

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第一作者： Muhammad Ali,Shahbaz

第一单位： A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland.

作者： Muhammad Ali,Shahbaz ^[1] ; Francesca,De Bernardi ^[2] ; Arto,Alatalo ^[1] ; Magdalini,Sachana ^[3] ; Laure-Alix,Clerbaux ^[4] ; Amalia,Muñoz ^[5] ; Surat,Parvatam ^[6] ; Brigitte,Landesmann ^[4] ; Katja M,Kanninen ^[1] ; Sandra,Coecke ^[4]

作者单位： A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, 70211 Kuopio, Finland. ^[1] Division of Otorhinolaryngology, Department of Biotechnologies and Life Sciences, University of Insubria, Ospedale di Circolo e Fondazione Macchi, 21100 Varese, Italy. ^[2] Environment Health and Safety Division, Environment Directorate, Organisation for Economic Cooperation and Development (OECD), 75775 Paris, France. ^[3] European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy. ^[4] European Commission, Joint Research Centre (JRC), 2440 Geel, Belgium. ^[5] Centre for Predictive Human Model Systems, Atal Incubation Centre-Centre for Cellular and Molecular Biology (AIC-CCMB), Habsiguda, Hyderabad 500039, India. ^[6]

关键词 AOP COVID-19 SARS-CoV-2 infection anosmia olfactory neuroepithelium

医学主题词人类(Humans);嗅觉障碍(Olfaction Disorders);嗅觉(Smell)

DOI 10.3390/cells11193027

PMID 36230989

发布时间 2024-10-05

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