Site-Specific Radioiodination of Oligonucleotides with a Phenolic Element in a Programmable Approach.

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作者： Haitao,Zhao ^[1] ; Yu,Qin ^[1] ; Dunfang,Liu ^[1] ; Xinyao,Geng ^[1] ; Cheng,Wang ^[1] ; Ding,Ding ^[1] ; Xuan,Ding ^[1] ; Qian,Xia ^[1] ; Jianjun,Liu ^[1] ; Ruowen,Wang ^[1] ; Weihong,Tan ^[1]

作者单位： Institute of Molecular Medicine (IMM), Institute of Clinical Nuclear Medicine, Department of Nuclear Medicine, Department of Pharmacy, State Key Laboratory of Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. ^[1] Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha 410082, China. ^[2]

关键词 aptamer oligonucleotide phosphoramidite radioiodination solid-phase synthesis

主题词 DNA(DNA);碘放射性同位素(Iodine Radioisotopes);核酸类(Nucleic Acids);寡核苷酸类(Oligonucleotides);酚类(Phenols);RNA(RNA)

DOI 10.3390/molecules27196257

PMID 36234794

发布时间 2022-10-19

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