Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 studies across 25 countries.

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作者： Xinxuan,Li ^[1] ; Yajing,Zhou ^[1] ; Shuai,Yuan ^[1] ; Xuan,Zhou ^[2] ; Lijuan,Wang ^[1] ; Jing,Sun ^[1] ; Lili,Yu ^[1] ; Jinghan,Zhu ^[1] ; Han,Zhang ^[3] ; Nan,Yang ^[1] ; Shuhui,Dai ^[1] ; Peige,Song ^[1] ; Susanna C,Larsson ^[4] ; Evropi,Theodoratou ^[2] ; Yimin,Zhu ^[5] ; Xue,Li ^[6]

作者单位： Department of Big Data in Health Science School of Public Health, Center of Clinical Big Data and Analytics of The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[1] Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. ^[2] The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China. ^[3] School of Public Health and Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[4] Unit of Medical Epidemiology, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden. ^[5] Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom. ^[6] Cancer Research UK Edinburgh Centre, Medical Research Council Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom. ^[7]

关键词 COVID-19 IGF-1 Mendelian randomization epidemiology global health sex hormones viruses