首页> Journal of affective disorders> Intranasal esketamine effectively treats treatment-resistant depression in adults regardless of baseline irritability.

Intranasal esketamine effectively treats treatment-resistant depression in adults regardless of baseline irritability.

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第一作者： Manish K,Jha

第一单位： Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, TX, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: manish.jha@utsouthwestern.edu.

作者： Manish K,Jha ^[1] ; David J,Williamson ^[2] ; Ghazal,Magharehabed ^[3] ; Ibrahim,Turkoz ^[4] ; Ella J,Daly ^[2] ; Madhukar H,Trivedi ^[5]

作者单位： Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, TX, USA; Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: manish.jha@utsouthwestern.edu. ^[1] Janssen Scientific Affairs, LLC, Titusville, NJ, USA. ^[2] Janssen Scientific Affairs, LLC, Titusville, NJ, USA. Electronic address: gmaghare@its.jnj.com. ^[3] Janssen Research & Development, LLC, Titusville, NJ, USA. Electronic address: iturkoz@its.jnj.com. ^[4] Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: madhukar.trivedi@utsouthwestern.edu. ^[5]

关键词 Antidepressant Depression Esketamine Irritability Major depressive disorder Treatment-resistant depression

医学主题词人类(Humans);成年人(Adult);鼻用喷雾剂(Nasal Sprays);抑郁(Depression);抗抑郁药(Antidepressive Agents);双盲法(Double-Blind Method);治疗结果(Treatment Outcome)

DOI 10.1016/j.jad.2022.10.020

PMID 36273682

发布时间 2023-02-16

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