Acid sensor ASIC1a induces synovial fibroblast proliferation via Wnt/β-catenin/c-Myc pathway in rheumatoid arthritis.

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第一作者： Yayun,Xu

第一单位： School of Public Health, Anhui Medical University, Hefei, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Hefei, China; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China.

作者： Yayun,Xu ^[1] ; Zheng,Lu ^[2] ; Yian,Ling ^[2] ; Ruirui,Hou ^[2] ; Jingjing,Tao ^[2] ; Ge,Deng ^[2] ; Xiaoling,Xu ^[2] ; Xuewei,Chen ^[3] ; Jingjing,Ruan ^[4] ; Yihao,Zhang ^[5] ; Xiaoqing,Peng ^[6] ; Feihu,Chen ^[7]

作者单位： School of Public Health, Anhui Medical University, Hefei, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Hefei, China; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China. ^[1] School of Pharmacy, Anhui Medical University, Hefei, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Hefei, China; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China. ^[2] School of Pharmacy, Anhui Medical University, Hefei, China. ^[3] Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, China. ^[4] Department of Toxicology, School of Public Health, Anhui Medical University, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, China. Electronic address: ahmuzyh@ahmu.edu.cn. ^[5] Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, China. Electronic address: pengxiaoqing@ahmu.edu.cn. ^[6] School of Public Health, Anhui Medical University, Hefei, China; School of Pharmacy, Anhui Medical University, Hefei, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Hefei, China; Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, China. Electronic address: chenfeihu@ahmu.edu.cn. ^[7]

关键词 ASIC1a Proliferation Rheumatoid arthritis Synovial fibroblasts Wnt/β-catenin pathway