Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury.

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第一作者： Yangyang,Li

第一单位： State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China.

作者： Yangyang,Li ^[1] ; Yuwen,Wen ^[1] ; Xiuxing,Liu ^[1] ; Zhuang,Li ^[1] ; Bingying,Lin ^[1] ; Caibin,Deng ^[1] ; Ziyu,Yu ^[1] ; Yingting,Zhu ^[1] ; Ling,Zhao ^[1] ; Wenru,Su ^[2] ; Yehong,Zhuo ^[3]

作者单位： State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. ^[1] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. suwr3@mail.sysu.edu.cn. ^[2] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, 510060, China. zhuoyh@mail.sysu.edu.cn. ^[3]

关键词 Fer-1 Ferroptosis Retinal ischemia–reperfusion injury Single-cell RNA sequencing

主题词小鼠(Mice);动物(Animals);再灌注损伤(Reperfusion Injury);疾病模型, 动物(Disease Models, Animal);缺血(Ischemia);序列分析, RNA(Sequence Analysis, RNA);铁(Iron)

DOI 10.1186/s12974-022-02621-9

PMID 36289494

发布时间 2022-10-30

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