Rapastinel accelerates loss of withdrawal signs after repeated morphine and blunts relapse to conditioned place preference.

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作者： Christopher,Armstrong ^[1] ; Julia,Ferrante ^[2] ; Nidesh,Lamichhane ^[2] ; Zachery,Reavis ^[2] ; David,Walker ^[2] ; Ashwin,Patkar ^[3] ; Cynthia,Kuhn ^[4]

作者单位： Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, United States of America. ^[1] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, United States of America; Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, United States of America. ^[2] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, United States of America; Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, United States of America; Avance Psychiatry, 7850 Brier Creek Pkwy, Ste. 102, Raleigh, NC 27617, United States of America. ^[3] Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, United States of America; Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, United States of America. Electronic address: ckuhn@duke.edu. ^[4]

关键词 Animal model Conditioned place preference Opioid dependence Opioid withdrawal Rapastinel