CIP2A deficiency promotes depression-like behaviors in mice through inhibition of dendritic arborization.

导出 OA

翻译打印收藏纠错

第一作者： Wen-Ting,Hu

第一单位： Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

作者： Wen-Ting,Hu ^[1] ; Zhen-Yu,Liuyang ^[2] ; Yuan,Tian ^[1] ; Jia-Wei,Liang ^[3] ; Xiao-Lin,Zhang ^[4] ; Hui-Liang,Zhang ^[1] ; Guan,Wang ^[1] ; Yuda,Huo ^[1] ; Yang-Ping,Shentu ^[4] ; Jian-Zhi,Wang ^[4] ; Xiao-Chuan,Wang ^[5] ; You-Ming,Lu ^[1] ; Jukka,Westermarck ^[1] ; Heng-Ye,Man ^[1] ; Rong,Liu ^[6]

作者单位： Department of Pathophysiology, Key Laboratory of Ministry of Education for Neurological Disorders, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[1] Department of Pathology, Peking University Shenzhen Hospital, Shenzhen, China. ^[2] Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China. ^[3] Department of Biology, Boston University, Boston, USA. ^[4] Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. ^[5] The Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, China. ^[6] Turku Bioscience Centre, University of Turku, Turku, Finland. ^[7] Åbo Akademi University, Turku, Finland. ^[8] Institute of Biomedicine, University of Turku, Turku, Finland. ^[9] Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[10]

关键词 AKT CIP2A PP2A dendritic arborization depression

主题词人类(Humans);小鼠(Mice);动物(Animals);抑郁症, 更年期(Depressive Disorder, Major);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);神经元(Neurons);神经元可塑性(Neuronal Plasticity)

DOI 10.15252/embr.202254911

PMID 36305233

发布时间 2023-10-29

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交