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Deep generative molecular design reshapes drug discovery.

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第一作者: Xiangxiang,Zeng
第一单位: College of Computer Science and Electronic Engineering, Hunan University, Changsha, Hunan 410082, P.R. China.
作者单位: College of Computer Science and Electronic Engineering, Hunan University, Changsha, Hunan 410082, P.R. China. [1] Department of Population Health Sciences, Weill Cornell Medical College, Cornell University, New York, NY 10065, USA. [2] Division of Health and Biomedical Informatics, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. [3] Healthcare & Life Sciences Research, IBM TJ Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598, USA. [4] Mila-Quebec Institute for Learning Algorithms and CIFAR AI Research Chair, HEC Montreal, Montréal, QC H3T 2A7, Canada. [5] Biosciences and Biotechnology Division, Physical and Life Sciences Directorate, Lawrence Livermore National Lab, Livermore, CA 94550, USA. [6] Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478 Lørenskog, Oslo, Norway; The Norwegian Centre on Healthy Ageing (NO-Age), Oslo, Norway. [7] Computational Structural Biology Section, Frederick National Laboratory for Cancer Research in the Laboratory of Cancer Immunometabolism, National Cancer Institute, Frederick, MD 21702, USA; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. [8] Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA. Electronic address: chengf@ccf.org. [9]
DOI 10.1016/j.xcrm.2022.100794
PMID 36306797
发布时间 2024-10-01
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Cell reports. Medicine

Cell reports. Medicine

2022年3卷12期

100794页

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