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Discovery and functional characterization of the oncogenicity and targetability of a novel <i>NOTCH1-ROS1</i> gene fusion in pediatric angiosarcoma.

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第一作者： Payal,Jain

第一单位： Center for Data Driven Discovery in Biomedicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.;Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.

作者： Payal,Jain ^[1] ; Sudarshan,Iyer ^[2] ; Joshua,Straka ^[1] ; Lea F,Surrey ^[3] ; Jennifer,Pogoriler ^[3] ; Harry,Han ^[1] ; Tiffany,Smith ^[1] ; Christine,Busch ^[4] ; Elizabeth,Fox ^[4] ; Marilyn,Li ^[3] ; Angela J,Waanders ^[5] ; Adam,Resnick ^[1] ; Monika A,Davare ^[2]

作者单位： Center for Data Driven Discovery in Biomedicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.;Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. ^[1] Department of Pediatrics, Oregon Health and Sciences University, Portland, Oregon 97239, USA. ^[2] Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.;Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. ^[3] Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA. ^[4] Department of Pediatrics, Feinberg School of Medicine Northwestern University, Chicago, Illinois 60611, USA.;Division of Hematology, Oncology, and Stem Cell Transplant, Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois 60611, USA. ^[5]

关键词 metastatic angiosarcoma