Sequential hydrolysis of FAD by ecto-5' nucleotidase CD73 and alkaline phosphatase is required for uptake of vitamin B<sub>2</sub> into cells.

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第一作者： Natsuki,Shichinohe

第一单位： Department of Food and Chemical Toxicology, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan.

作者： Natsuki,Shichinohe ^[1] ; Daisuke,Kobayashi ^[2] ; Ayaka,Izumi ^[1] ; Kazuya,Hatanaka ^[1] ; Rio,Fujita ^[1] ; Taroh,Kinoshita ^[3] ; Norimitsu,Inoue ^[4] ; Naoya,Hamaue ^[1] ; Keiji,Wada ^[1] ; Yoshiko,Murakami ^[5]

作者单位： Department of Food and Chemical Toxicology, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan. ^[1] Department of Food and Chemical Toxicology, School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan. Electronic address: kobadai@hoku-iryo-u.ac.jp. ^[2] Laboratory of Immunoglycobiology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan; WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan; Center for Infectious Disease Education and Research, Osaka University, Suita, Osaka, Japan. ^[3] Department of Molecular Genetics, Wakayama Medical University, Wakayama, Wakayama, Japan. ^[4] Laboratory of Immunoglycobiology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan; WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan. Electronic address: yoshiko@biken.osaka-u.ac.jp. ^[5]

关键词 flavin mononucleotide (FMN)glycosylphosphatidylinositol (GPI anchor)phosphatase riboflavin vitamin