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Germ line DDX41 mutations define a unique subtype of myeloid neoplasms.

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作者单位: Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan. [1] Departments of Medicine and Human Genetics, Section of Hematology/Oncology, The University of Chicago, Chicago, IL. [2] Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.;Department of Biomedicine and Prevention, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy. [3] Laboratory for Genotyping Development, Center for Integrative Medical Sciences (IMS), RIKEN, Yokohama, Japan. [4] King's College Hospital NHS Foundation Trust, and King's College London, London, United Kingdom. [5] Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan. [6] Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.;Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo, Japan. [7] Department of Advanced Diagnosis, Clinical Research Center, Nagoya Medical Center, Nagoya, Japan. [8] National Cancer Center Research Institute, Division of Genome Analysis Platform Development, Tokyo, Japan. [9] Department of Hematology and Oncology, Tokai University School of Medicine, Isehara, Japan. [10] Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. [11] Department of Hematology, Atomic Bomb Disease and Hibakusha Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan. [12] Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan. [13] Department of Hematology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan. [14] Department of Hematology, Gifu University, Gifu, Japan. [15] Department of Hematology, Gifu Municipal Hospital, Gifu, Japan. [16] Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany. [17] Department of Hematology, Kyoto University, Kyoto, Japan. [18] Department of Hematology, Tokyo Medical University, Tokyo, Japan. [19] Chugoku Central Hospital, Fukuyama, Japan. [20] Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan. [21] Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands. [22] Department of Medicine, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand. [23] Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. [24] Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. [25] National Cancer Center Research Institute, Division of Genome Analysis Platform Development, Tokyo, Japan.;Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.;Medical and Dental, Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan. [26] Department of Molecular Medicine, University of Pavia, Pavia, Italy. [27] MLL Munich Leukemia Laboratory, Munich, Germany. [28] Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. [29] Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH. [30] Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.;Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.;Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden. [31]
DOI 10.1182/blood.2022018221
PMID 36322930
发布时间 2024-08-01
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