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A genetically encoded fluorescent biosensor for detecting itaconate with subcellular resolution in living macrophages.

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第一作者： Pengkai,Sun

第一单位： CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.;College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.

作者： Pengkai,Sun ^[1] ; Zhenxing,Zhang ^[2] ; Bin,Wang ^[1] ; Caiyun,Liu ^[1] ; Chao,Chen ^[2] ; Ping,Liu ^[2] ; Xinjian,Li ^[3]

作者单位： CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.;College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. ^[1] CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. ^[2] CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. lixinjian@ibp.ac.cn.;College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China. lixinjian@ibp.ac.cn. ^[3]

医学主题词小鼠(Mice);动物(Animals);脂多糖类(Lipopolysaccharides);琥珀酸盐(Succinates);巨噬细胞(Macrophages);生物传感技术(Biosensing Techniques)

DOI 10.1038/s41467-022-34306-5

PMID 36333306

发布时间 2022-12-24

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