The individuality paradigm: Automated longitudinal activity tracking of large cohorts of genetically identical mice in an enriched environment.

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第一作者： Gerd,Kempermann

第一单位： German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, TU Dresden, Dresden, Germany. Electronic address: gerd.kempermann@dzne.de.

作者： Gerd,Kempermann ^[1] ; Jadna Bogado,Lopes ^[2] ; Sara,Zocher ^[2] ; Susan,Schilling ^[2] ; Fanny,Ehret ^[3] ; Alexander,Garthe ^[2] ; Anne,Karasinsky ^[2] ; Andreas M,Brandmaier ^[4] ; Ulman,Lindenberger ^[4] ; York,Winter ^[5] ; Rupert W,Overall ^[6]

作者单位： German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, TU Dresden, Dresden, Germany. Electronic address: gerd.kempermann@dzne.de. ^[1] German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, TU Dresden, Dresden, Germany. ^[2] German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, TU Dresden, Dresden, Germany; Institute of Anatomy, TU Dresden, Dresden, Germany. ^[3] Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Max Planck UCL Centre for Computational Psychiatry and Ageing Research, Berlin, Germany. ^[4] Institute of Biology, Humboldt University, Berlin, Germany; Charité University Medicine, Berlin, Germany. ^[5] German Center for Neurodegenerative Diseases (DZNE) Dresden, Dresden, Germany; CRTD - Center for Regenerative Therapies Dresden, TU Dresden, Dresden, Germany; Institute of Biology, Humboldt University, Berlin, Germany. ^[6]

关键词 Aging Behavior Brain Environmental enrichment Gene environment interaction Home-cage tracking Individuation Longitudinal Non-shared environment Plasticity

主题词动物(Animals);小鼠(Mice);个性(Individuality);神经元可塑性(Neuronal Plasticity)

DOI 10.1016/j.nbd.2022.105916

PMID 36336243

发布时间 2022-12-22

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