Simultaneous modeling prediction of three key quality attributes of tablets by powder physical properties.

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第一作者： Cheng,Jin

第一单位： College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, No. 1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China.

作者： Cheng,Jin ^[1] ; Lijie,Zhao ^[2] ; Yi,Feng ^[3] ; Yanlong,Hong ^[4] ; Lan,Shen ^[1] ; Xiao,Lin ^[5]

作者单位： College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, No. 1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China. ^[1] Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine of Ministry of Education, Shanghai University of Traditional Chinese Medicine, No.1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China. Electronic address: zhaolijie761029@126.com. ^[2] Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine of Ministry of Education, Shanghai University of Traditional Chinese Medicine, No.1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China. ^[3] Shanghai Innovation Center of Traditional Chinese Medicine Health Service, Shanghai University of Traditional Chinese Medicine, No.1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China. ^[4] College of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, No. 1200, Cai Lun Road, Pudong District, Shanghai 201203, PR China. Electronic address: duotang@163.com. ^[5]

关键词 Model Powder physical properties Solid fraction Tablet quality Tablet weight variability Tensile strength

主题词粉剂(Powders);片剂(Tablets);拉伸强度(Tensile Strength);最小二乘法分析(Least-Squares Analysis);主成分分析(Principal Component Analysis);药物调剂(Drug Compounding)

DOI 10.1016/j.ijpharm.2022.122344

PMID 36341919

发布时间 2022-11-15

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