Cryo-EM of prion strains from the same genotype of host identifies conformational determinants.

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作者： Forrest,Hoyt ^[1] ; Parvez,Alam ^[2] ; Efrosini,Artikis ^[2] ; Cindi L,Schwartz ^[1] ; Andrew G,Hughson ^[2] ; Brent,Race ^[2] ; Chase,Baune ^[2] ; Gregory J,Raymond ^[2] ; Gerald S,Baron ^[2] ; Allison,Kraus ^[3] ; Byron,Caughey ^[2]

作者单位： Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America. ^[1] Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America. ^[2] Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America.;Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America. ^[3]

主题词动物(Animals);小鼠(Mice);冷冻电子显微镜检查(Cryoelectron Microscopy);基因型(Genotype);朊病毒(Prions);蛋白质构象(Protein Conformation)

DOI 10.1371/journal.ppat.1010947

PMID 36342968

发布时间 2024-09-07

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