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Analysis of matched primary and recurrent BRCA1/2 mutation-associated tumors identifies recurrence-specific drivers.

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第一作者: Jennifer B,Shah
第一单位: Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.
作者单位: Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. [1] Experimental Therapeutics Group, Vall d'Hebron Institut d'Oncologia, Barcelona, Spain. [2] Hereditary Cancer Genetics Group, Vall d'Hebron Institut d'Oncologia, Barcelona, Spain.;Department of Medical Oncology, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain. [3] Division of Surgical Pathology, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.;Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. [4] Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. [5] Division of Surgical Pathology, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. [6] Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.;Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.;Basser Center for BRCA, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. [7] Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. knathans@upenn.edu.;Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. knathans@upenn.edu.;Basser Center for BRCA, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA. knathans@upenn.edu. [8]
DOI 10.1038/s41467-022-34523-y
PMID 36344544
发布时间 2024-09-07
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