MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.

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第一作者： Francisco M,Barriga

第一单位： Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

作者： Francisco M,Barriga ^[1] ; Kaloyan M,Tsanov ^[1] ; Yu-Jui,Ho ^[1] ; Noor,Sohail ^[2] ; Amy,Zhang ^[3] ; Timour,Baslan ^[1] ; Alexandra N,Wuest ^[1] ; Isabella,Del Priore ^[4] ; Brigita,Meškauskaitė ^[2] ; Geulah,Livshits ^[1] ; Direna,Alonso-Curbelo ^[1] ; Janelle,Simon ^[1] ; Almudena,Chaves-Perez ^[1] ; Dafna,Bar-Sagi ^[5] ; Christine A,Iacobuzio-Donahue ^[6] ; Faiyaz,Notta ^[7] ; Ronan,Chaligne ^[2] ; Roshan,Sharma ^[2] ; Dana,Pe'er ^[2] ; Scott W,Lowe ^[8]

作者单位： Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ^[1] Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ^[2] PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada. ^[3] Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, New York, NY, USA. ^[4] Department of Biochemistry, New York University School of Medicine, New York, NY, USA. ^[5] David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA. ^[6] PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.;Division of Research, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.;Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. ^[7] Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. lowes@mskcc.org.;Howard Hughes Medical Institute, Chevy Chase, MD, USA. lowes@mskcc.org. ^[8]

主题词动物(Animals);小鼠(Mice);染色体缺失(Chromosome Deletion);染色体(Chromosomes);免疫逃避(Immune Evasion);干扰素类(Interferons);肿瘤(Neoplasms);肿瘤微环境(Tumor Microenvironment);串联重复序列(Tandem Repeat Sequences)

DOI 10.1038/s43018-022-00443-5

PMID 36344707

发布时间 2024-10-23

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Nature cancer

2022年3卷11期

1367-1385页

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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.

Nature cancer

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MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.

Nature cancer

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Nature cancer

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