首页> International journal of molecular sciences> Molecular and Functional Characterization of BDNF-Overexpressing Human Retinal Pigment Epithelial Cells Established by <i>Sleeping Beauty</i> Transposon-Mediated Gene Transfer.

Molecular and Functional Characterization of BDNF-Overexpressing Human Retinal Pigment Epithelial Cells Established by <i>Sleeping Beauty</i> Transposon-Mediated Gene Transfer.

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第一作者： Larissa,Mattern

第一单位： Department of Ophthalmology, University Hospital RWTH Aachen, 52074 Aachen, Germany.

作者： Larissa,Mattern ^[1] ; Katrin,Otten ^[1] ; Csaba,Miskey ^[2] ; Matthias,Fuest ^[1] ; Zsuzsanna,Izsvák ^[3] ; Zoltán,Ivics ^[2] ; Peter,Walter ^[1] ; Gabriele,Thumann ^[4] ; Sandra,Johnen ^[1]

作者单位： Department of Ophthalmology, University Hospital RWTH Aachen, 52074 Aachen, Germany. ^[1] Division of Medical Biotechnology, Paul-Ehrlich-Institute, 63225 Langen, Germany. ^[2] Max Delbrück Center for Molecular Medicine in the Helmholtz Association, 13125 Berlin, Germany. ^[3] Department of Ophthalmology, University Hospitals of Geneva, 1205 Geneva, Switzerland.;Experimental Ophthalmology, University of Geneva, 1205 Geneva, Switzerland. ^[4]

关键词 AMD BDNF RPE cells Sleeping Beauty transposon system cell-based additive gene therapy neurodegenerative retinal diseases non-viral transfection

医学主题词人类(Humans);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);视网膜色素上皮(Retinal Pigment Epithelium);神经母细胞瘤(Neuroblastoma);上皮细胞(Epithelial Cells);视网膜色素类(Retinal Pigments)

DOI 10.3390/ijms232112982

PMID 36361771

发布时间 2022-11-17

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