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Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer.

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第一作者: Laura,Devis-Jauregui
第一单位: Molecular Mechanisms and Experimental Therapy in Oncology-Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.
作者单位: Molecular Mechanisms and Experimental Therapy in Oncology-Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain. [1] Department of Pathology, University Hospital of Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain. [2] Scientific and Technical Service of Immunohistochemistry, Lleida Institute for Biomedical Research Dr. Pifarré Foundation, IRBLleida, Hospital Universitari Arnau de Vilanova, Lleida, 25198, Spain.;Department of Pathology, Universitat de Lleida/Institut de Recerca Biomèdica de Lleida/Hospital Universitari Arnau de Vilanova, Lleida, 25198, Spain. [3] Unit of Biomarkers and Susceptibility, Oncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL) and CIBERESP, L'Hospitalet de Llobregat, Barcelona, 08908, Spain. [4] Department of Basic Sciences, Universitat de Lleida/Institut de Recerca Biomèdica de Lleida, Edifici Biomedicina I, Lab 2.4, Lleida, 25198, Spain.;Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, (ISCIII), Madrid, 28029, Spain. [5] Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat Barcelona, Barcelona, 08908, Spain. [6] Molecular Mechanisms and Experimental Therapy in Oncology-Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, (ISCIII), Madrid, 28029, Spain. [7] Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain. [8] Molecular Mechanisms and Experimental Therapy in Oncology-Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Anatomy Unit, Department of Pathology and Experimental Therapy, School of Medicine, University of Barcelona (UB), L'Hospitalet de Llobregat, Barcelona, 08907, Spain. [9] Department of Gynaecology, University Hospital of Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain. [10] Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Department of Physiological Sciences, School of Medicine, University of Barcelona (UB), L'Hospitalet de Llobregat, Barcelona, 08907, Spain. [11] Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, (ISCIII), Madrid, 28029, Spain.;Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat Barcelona, Barcelona, 08908, Spain. [12] Cancer Genomics Group, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, 08035, Spain. [13] Molecular Mechanisms and Experimental Therapy in Oncology-Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Department of Pathology, University Hospital of Bellvitge, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Scientific and Technical Service of Immunohistochemistry, Lleida Institute for Biomedical Research Dr. Pifarré Foundation, IRBLleida, Hospital Universitari Arnau de Vilanova, Lleida, 25198, Spain.;Department of Pathology, Universitat de Lleida/Institut de Recerca Biomèdica de Lleida/Hospital Universitari Arnau de Vilanova, Lleida, 25198, Spain.;Department of Basic Sciences, Universitat de Lleida/Institut de Recerca Biomèdica de Lleida, Edifici Biomedicina I, Lab 2.4, Lleida, 25198, Spain.;Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, (ISCIII), Madrid, 28029, Spain. [14] Chemoresistance and Predictive Factors Group, Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.;Xenopat S.L., Parc Cientific de Barcelona (PCB), Barcelona, 08028, Spain. [15]
DOI 10.1002/advs.202204211
PMID 36373729
发布时间 2024-09-10
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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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