首页> Pain> Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice.

Novel proresolving lipid mediator mimetic 3-oxa-PD1n-3 docosapentaenoic acid reduces acute and chronic itch by modulating excitatory and inhibitory synaptic transmission and astroglial secretion of lipocalin-2 in mice.

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第一作者： Kenta,Furutani

第一单位： Center for Translational Pain Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC, United States.

作者： Kenta,Furutani ^[1] ; Ouyang,Chen ^[2] ; Aidan,McGinnis ^[1] ; Yuqing,Wang ^[1] ; Charles N,Serhan ^[3] ; Trond Vidar,Hansen ^[4] ; Ru-Rong,Ji ^[5]

作者单位： Center for Translational Pain Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC, United States. ^[1] Center for Translational Pain Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC, United States.;Department of Cell Biology, Duke University Medical Center, Durham, NC, United States. ^[2] Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Hale Building for Transformative Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States. ^[3] Department of Pharmacy, Section for Pharmaceutical Chemistry, University of Oslo, Oslo, Norway. ^[4] Center for Translational Pain Medicine, Department of Anesthesiology, and Department of Neurobiology, Duke University Medical Center, Durham, NC, United States.;Department of Cell Biology, Duke University Medical Center, Durham, NC, United States.;Department of Neurobiology, Duke University Medical Center, Durham, NC, United States. ^[5]