Sarcoma classification by DNA methylation profiling in clinical everyday life: the Charité experience.

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作者： Siyer,Roohani ^[1] ; Felix,Ehret ^[2] ; Eilís,Perez ^[3] ; David,Capper ^[4] ; Armin,Jarosch ^[5] ; Anne,Flörcken ^[4] ; Sven,Märdian ^[5] ; Daniel,Zips ^[6] ; David,Kaul ^[4]

作者单位： Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology, Augustenburger Platz 1, 13353, Berlin, Germany. siyer.roohani@charite.de. ^[1] Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Radiation Oncology, Augustenburger Platz 1, 13353, Berlin, Germany. ^[2] Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany. ^[3] Charité - Universitätsmedizin Berlin, Berlin, German Cancer Consortium (DKTK), partner site Berlin, and German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany. ^[4] Department of Neuropathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‑Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. ^[5] Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. ^[6] Department of Hematology, Oncology and Tumor Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. ^[7] Centre for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353, Berlin, Germany. ^[8]

关键词 Bone Classifier Clinical experience DNA methylation Methylation profiling Profiling Sarcoma Soft tissue

主题词人类(Humans);DNA甲基化(DNA Methylation);肉瘤(Sarcoma);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);诊断, 鉴别(Diagnosis, Differential)

DOI 10.1186/s13148-022-01365-w

PMID 36380356

发布时间 2023-01-25

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