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Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature.

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第一作者: Yusuke,Shimizu
第一单位: Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Nakagami, Okinawa, 903-0215, Japan.
作者单位: Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Nakagami, Okinawa, 903-0215, Japan. [1] Center for Advanced Medical Research, School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Nakagami, Okinawa, 903-0215, Japan. [2] Department of Plastic and Reconstructive Surgery, School of Medicine, Fujita Health University, 1-98, Dengakugakubo, Kutsukake, Toyoake, Aichi, 470-1192, Japan. [3]
关键词 AA, alopecia areataAA-PRP, autologous activated PRPAD-MSCs, adipose tissue derived mesenchymal stromal cellsADRCs, adipose-derived regenerative cellsADSVCs, adipose-derived stromal vascular cellsAE, anagen effluviumAGA, androgenetic alopeciaAlopeciaBM-MSCs, bone marrow derived mesenchymal stromal cellsCA, cicatricial alopeciaCD, cluster of differentiationCM, conditioned mediumDHT, dihydrotestosteroneECM, extracellular matrixEGF, epidermal growth factorEMA, European Medicines AgencyEMI, epithelial–mesenchymal interactionEVs, extracellular vesiclesFDA, United States Food and Drug AdministrationFGF, fibroblast growth factorFPHL, female-pattern hair lossGMP, good manufacturing practiceGVHD, graft-versus-host diseaseHF, hair follicleHFSCs, hair follicle stem cellsHair follicle regenerationHair lossHair regrowthIGF, insulin-like growth factorIL, interleukinISSCR, The International Society for Stem Cell ResearchKGF, keratinocyte growth factorLA, lipedematous alopeciaLS, lipedematous scalpMAPK/ERK, mitogen-activated protein kinases or extracellular signal-regulated kinasesMCP1, monocyte chemoattractant protein 1MMP, matrix metalloproteinaseMPHL, male-pattern hair lossMSCs, mesenchymal stromal cellsOS, oxidative stressPDGF, platelet-derived growth factorPG, prostaglandinPI3K/Akt, phosphatidylinositol 3-kinase/protein kinase BPMD-Act, pharmaceuticals and Medical Devices Agency-ActPRP, platelet-rich plasmaROS, reactive oxygen speciesSALT, severity of alopecia toolSCs, stem cellsSLE, systemic lupus erythematosusSVF, stromal vascular fractionStem cell extracellular vesiclesStem cell therapyTA, traction alopeciaTE, telogen effluviumTGF-β, transforming growth factor βTNF, tumor necrosis factorTTM, trichotillomaniaTh, T helperTreg, regulatory T cellsVEGF, vascular endothelial growth factorWnt, wingless/integrated-1hDPCs, human dermal papilla cellshUC-MSCs, umbilical cord blood-derived mesenchymal stromal cellsiPSC-MSCs, induced pluripotent stem cells derived mesenchymal stem cellsiPSCs, induced pluripotent stem cellsnon-CA, non-cicatricial alopecia
DOI 10.1016/j.reth.2022.10.005
PMID 36382136
发布时间 2022-11-17
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Regenerative therapy

Regenerative therapy

2022年21卷

527-539页

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