首页> Cytotechnology> A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1.

A novel matrine derivative, WM130, inhibits activation and movement of human hepatic stellate LX-2 cells by targeting cofilin 1.

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第一作者： Yang,Xu

第一单位： Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437 China.;Department of Molecular Oncology, Eastern Hepatobiliary Surgery Hospital and National Center of Liver Cancer, Navy Military Medical University, Shanghai, 200438 China.

作者： Yang,Xu ^[1] ; Jicheng,Duan ^[2] ; Weidan,Ji ^[2] ; Chao,Liu ^[3] ; Xiang,Li ^[3] ; Qiuye,Wu ^[3] ; Chunfang,Gao ^[4] ; Changqing,Su ^[2]

作者单位： Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437 China.;Department of Molecular Oncology, Eastern Hepatobiliary Surgery Hospital and National Center of Liver Cancer, Navy Military Medical University, Shanghai, 200438 China. ^[1] Department of Molecular Oncology, Eastern Hepatobiliary Surgery Hospital and National Center of Liver Cancer, Navy Military Medical University, Shanghai, 200438 China. ^[2] Department of Pharmacy, Navy Military Medical University, Shanghai, 200438 China. ^[3] Clinical Laboratory Medicine Center, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437 China. ^[4]

关键词 Cofilin 1 Hepatic stellate cells LX-2 cell line Liver fibrosis Novel matrine derivative WM130

DOI 10.1007/s10616-022-00548-w

PMID 36389285

发布时间 2023-12-02

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