<i>HLA-DRB1*1501</i> influences long-term disability progression and tissue damage on MRI in relapse-onset multiple sclerosis.

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作者： Wallace J,Brownlee ^[1] ; Carmen,Tur ^[2] ; Andreea,Manole ^[3] ; Arman,Eshaghi ^[1] ; Ferran,Prados ^[4] ; Katherine A,Miszkiel ^[5] ; Claudia Am Gandini,Wheeler-Kingshott ^[6] ; Henry,Houlden ^[7] ; Olga,Ciccarelli ^[8]

作者单位： NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK. ^[1] NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK/UK e-Health Center, Universitat Oberta de Catalunya, Barcelona, Spain. ^[2] Salk Institute for Biological Studies, San Diego, CA, USA. ^[3] NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK/Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, UK. ^[4] Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, London, UK. ^[5] NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK/Brain Connectivity Center, C. Mondino National Neurological Institute, Pavia, Italy Department of Brain and Behavioural Sciences, University of Pavia, Pavia, Italy. ^[6] Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK/NIHR University College London Hospitals Biomedical Research Centre, London, UK. ^[7] NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London, UK/NIHR University College London Hospitals Biomedical Research Centre, London. ^[8]

关键词 Clinically isolated syndrome genetics multiple sclerosis prognosis

主题词人类(Humans);多发性硬化(Multiple Sclerosis);肿瘤复发, 局部(Neoplasm Recurrence, Local);脱髓鞘疾病(Demyelinating Diseases);磁共振成像(Magnetic Resonance Imaging);慢性病(Chronic Disease);疾病遗传易感性(Genetic Predisposition to Disease)

DOI 10.1177/13524585221130941

PMID 36398585

发布时间 2023-02-28

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