Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma.

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作者： Amelia L,Parker ^[1] ; Elise,Bowman ^[2] ; Adriana,Zingone ^[3] ; Brid M,Ryan ^[3] ; Wendy A,Cooper ^[3] ; Maija,Kohonen-Corish ^[4] ; Curtis C,Harris ^[5] ; Thomas R,Cox ^[6]

作者单位： Matrix and Metastasis Lab, Cancer Ecosystems Program, Garvan Institute of Medical Research and The Kinghorn Cancer Centre, 384 Victoria St, Darlinghurst, NSW, 2052, Australia. Am.parker@garvan.org.au. ^[1] School of Clinical Medicine, UNSW Sydney, Sydney, 2052, Australia. Am.parker@garvan.org.au. ^[2] Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, 20892, USA. ^[3] Present address: MiNA Therapeutics, London, UK. ^[4] Department of Tissue Pathology and Diagnostic Oncology, NSW Health Pathology, Royal Prince Alfred Hospital, Camperdown, NSW, 2050, Australia. ^[5] Sydney Medical School, University of Sydney, Sydney, NSW, 2050, Australia. ^[6] Discipline of Pathology, School of Medicine, Western Sydney University, Liverpool, NSW, 2170, Australia. ^[7] Woolcock Institute of Medical Research, Sydney, NSW, 2037, Australia. ^[8] Microbiome Research Centre, School of Clinical Medicine, UNSW Sydney, Sydney, 2052, Australia. ^[9] Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia. ^[10] Matrix and Metastasis Lab, Cancer Ecosystems Program, Garvan Institute of Medical Research and The Kinghorn Cancer Centre, 384 Victoria St, Darlinghurst, NSW, 2052, Australia. t.cox@garvan.org.au. ^[11] School of Clinical Medicine, UNSW Sydney, Sydney, 2052, Australia. t.cox@garvan.org.au. ^[12]

关键词 Extracellular matrix Non-small cell lung cancer Squamous

主题词人类(Humans);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);肺肿瘤(Lung Neoplasms);特发性肺纤维化(Idiopathic Pulmonary Fibrosis);癌, 鳞状细胞(Carcinoma, Squamous Cell);预后(Prognosis);细胞外基质(Extracellular Matrix)

DOI 10.1186/s13073-022-01127-6

PMID 36404344

发布时间 2023-01-05

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