The plasma free fraction of 25-hydroxyvitamin D<sub>3</sub> is not strongly associated with 25-hydroxyvitamin D<sub>3</sub> clearance in kidney disease patients and controls.

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第一作者： Cora M,Best

第一单位： Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA; Kidney Research Institute, University of Washington, Seattle, WA, USA. Electronic address: corabest@ufl.edu.

作者： Cora M,Best ^[1] ; Kenneth E,Thummel ^[2] ; Simon,Hsu ^[3] ; Yvonne,Lin ^[2] ; Leila R,Zelnick ^[4] ; Bryan,Kestenbaum ^[5] ; Mark M,Kushnir ^[6] ; Ian H,de Boer ^[7] ; Andrew N,Hoofnagle ^[8]

作者单位： Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA; Kidney Research Institute, University of Washington, Seattle, WA, USA. Electronic address: corabest@ufl.edu. ^[1] Department of Pharmaceutics, University of Washington, Seattle, WA, USA. ^[2] Kidney Research Institute, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA. ^[3] Kidney Research Institute, University of Washington, Seattle, WA, USA. ^[4] Kidney Research Institute, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA. ^[5] ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, UT, USA; Department of Pathology, University of Utah, Salt Lake City, UT, USA. ^[6] Kidney Research Institute, University of Washington, Seattle, WA, USA; Department of Medicine, University of Washington, Seattle, WA, USA; Puget Sound VA Healthcare System, Seattle, WA, USA. ^[7] Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA; Kidney Research Institute, University of Washington, Seattle, WA, USA; Department of Pharmaceutics, University of Washington, Seattle, WA, USA. ^[8]

关键词 25-hydroxyvitamin D Clearance Kidney disease Liquid chromatography-tandem mass spectrometry Pharmacokinetics