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Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection.

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第一作者： Yosuke,Morodomi

第一单位： Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037.;The Scripps Laboratories for tRNA Synthetase Research, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037.

作者： Yosuke,Morodomi ^[1] ; Sachiko,Kanaji ^[1] ; Brian M,Sullivan ^[2] ; Alessandro,Zarpellon ^[3] ; Jennifer N,Orje ^[4] ; Eric,Won ^[5] ; Ryan,Shapiro ^[6] ; Xiang-Lei,Yang ^[6] ; Wolfram,Ruf ^[7] ; Paul,Schimmel ^[6] ; Zaverio M,Ruggeri ^[4] ; Taisuke,Kanaji ^[1]

作者单位： Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037.;The Scripps Laboratories for tRNA Synthetase Research, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037. ^[1] Viral-Immunobiology Laboratory, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037. ^[2] MERU-VasImmune, Inc., San Diego, CA 92121. ^[3] Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037.;MERU-VasImmune, Inc., San Diego, CA 92121. ^[4] Department of Molecular Medicine, MERU-Roon Research Center on Vascular Biology, The Scripps Research Institute, La Jolla, CA 92037.;Department of Hematology and Oncology, University of California, San Diego, CA 92093.;Rady Children's Hospital, San Diego, CA 92123. ^[5] The Scripps Laboratories for tRNA Synthetase Research, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037. ^[6] Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, 55128 Germany.;Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037. ^[7]

关键词 inflammatory stress megakaryocyte platelet tyrosyl-tRNA synthetase viral infection