首页> Cellular oncology (Dordrecht, Netherlands)> Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progression.

Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progression.

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第一作者： Wei,Song

第一单位： Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, People's Republic of China.;School of Medicine, Kunming University of Science and Technology, Kunming, 650500, Yunnan, People's Republic of China.;Department of Radiology, The First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, People's Republic of China.

作者： Wei,Song ^[1] ; Haixi,Zhang ^[2] ; Fan,Yang ^[3] ; Kiichi,Nakahira ^[4] ; Cheng,Wang ^[5] ; Keqian,Shi ^[6] ; Ruoyu,Zhang ^[7]

作者单位： Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, Yunnan, People's Republic of China.;School of Medicine, Kunming University of Science and Technology, Kunming, 650500, Yunnan, People's Republic of China.;Department of Radiology, The First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, People's Republic of China. ^[1] Department of Hematology, The First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, People's Republic of China.;Yunnan Province Clinical Center for Hematologic Disease, Kunming, 650032, Yunnan, People's Republic of China.;Yunnan Province Clinical Research Center for Hematologic Disease, Kunming, 650032, Yunnan, People's Republic of China. ^[2] School of Medicine, Kunming University of Science and Technology, Kunming, 650500, Yunnan, People's Republic of China. ^[3] Department of Pharmacology, Nara Medical University, Kashihara, Nara, 634-8521, Japan.;Division of Pulmonary and Critical Care Medicine, Weill Department of Medicine, Joan and Sanford I, Weill Cornell Medicine, New York, NY, 10065, USA. ^[4] Innovec Biotherapeutics, Inc., Beijing, 100193, People's Republic of China. ^[5] Department of Hematology, The First People's Hospital of Yunnan Province, Kunming, 650032, Yunnan, People's Republic of China. shikeqian1@outlook.com.;Yunnan Province Clinical Center for Hematologic Disease, Kunming, 650032, Yunnan, People's Republic of China. shikeqian1@outlook.com.;Yunnan Province Clinical Research Center for Hematologic Disease, Kunming, 650032, Yunnan, People's Republic of China. shikeqian1@outlook.com. ^[6] Innovec Biotherapeutics, Inc., Beijing, 100193, People's Republic of China. zry0510@gmail.com. ^[7]

关键词 Hepatosplenic T-cell lymphoma Single cell RNA-seq Single cell TCR-seq γδ T cells

医学主题词人类(Humans);淋巴瘤, T细胞(Lymphoma, T-Cell);受体, 抗原, T细胞, γ-δ(Receptors, Antigen, T-Cell, gamma-delta);肝肿瘤(Liver Neoplasms);脾肿瘤(Splenic Neoplasms);疾病恶化(Disease Progression);肿瘤微环境(Tumor Microenvironment)

DOI 10.1007/s13402-022-00745-x

PMID 36417130

发布时间 2026-04-29

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