Structural Characterization and In Vivo Anti-Inflammatory Activity of Fucoidan from <i>Cystoseira crinita</i> (Desf.) Borry.

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作者： Elisaveta,Apostolova ^[1] ; Paolina,Lukova ^[2] ; Alexandra,Baldzhieva ^[3] ; Cédric,Delattre ^[4] ; Roland,Molinié ^[5] ; Emmanuel,Petit ^[6] ; Redouan,Elboutachfaiti ^[7] ; Mariana,Nikolova ^[7] ; Ilia,Iliev ^[7] ; Marianna,Murdjeva ^[8] ; Vesela,Kokova ^[8]

作者单位： Department of Pharmacology, Toxicology, and Pharmacotherapy, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[1] Department of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[2] Department of Microbiology and Immunology, Faculty of Pharmacy, Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[3] Research Institute at Medical University-Plovdiv, Vasil Aprilov Str. 15A, 4002 Plovdiv, Bulgaria. ^[4] Clermont Auvergne INP, CNRS, Institut Pascal, Université Clermont Auvergne, 63000 Clermont-Ferrand, France. ^[5] Institut Universitaire de France (IUF), 1 rue Descartes, 75005 Paris, France. ^[6] UMRT INRAE 1158 BioEcoAgro, BIOlogie des Plantes et Innovation (BIOPI), Avenue des Facultés, IUT d'Amiens, Université de Picardie Jules Verne, Le Bailly, 80025 Amiens, France. ^[7] Department of Biochemistry and Microbiology, Faculty of Biology, Plovdiv University Paisii Hilendarski, Tsar Asen Str. 24, 4000 Plovdiv, Bulgaria. ^[8]

关键词 Cystoseira?crinita IL-1β TNF-α anti-inflammatory effect cytokines fucoidan peritonitis rat paw edema