An update on molecular features and therapeutic perspectives of pediatric classical Hodgkin Lymphoma. What the clinician needs to know?

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作者： Mathieu,Simonin ^[1] ; Fabrice,Jardin ^[2] ; Thierry,Leblanc ^[3] ; Sylvain,Latour ^[4] ; Judith,Landman Parker ^[5]

作者单位： Department of Pediatric Hematology and Oncology, AP-HP, Armand Trousseau Hospital, Sorbonne University, Paris, France; Laboratory of Normal and Pathological Lymphoid Differentiation, Institut Necker Enfants Malades (INEM), INERM UMR1151, Paris, France; Laboratory of Lymphocyte Activation and Susceptibility to EBV Infection, INSERM UMR1163, Imagine Institute, Paris, France; Université de Paris, Paris, France. Electronic address: mathieu.simonin@aphp.fr. ^[1] Department of Hematology, Center Henri Becquerel, University of Rouen, INSERM UMR1245, Rouen, France. ^[2] Department of Pediatric Hematology, AP-HP, Robert Debré Hospital, University Paris Diderot, Paris, France. ^[3] Laboratory of Lymphocyte Activation and Susceptibility to EBV Infection, INSERM UMR1163, Imagine Institute, Paris, France; Université de Paris, Paris, France. ^[4] Department of Pediatric Hematology and Oncology, AP-HP, Armand Trousseau Hospital, Sorbonne University, Paris, France. ^[5]

关键词 Genetic predispositions Hodgkin lymphoma Liquid biopsy Mutational landscape Pediatric

主题词成年人(Adult);人类(Humans);儿童(Child);霍奇金病(Hodgkin Disease);抗肿瘤药(Antineoplastic Agents)

DOI 10.1016/j.ejmg.2022.104672

PMID 36423786

发布时间 2022-12-22

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