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TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.

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作者单位: Biomedical Center Munich (BMC), Department of Cell Biology and Anatomy, Medical Faculty, LMU, Munich, Germany. [1] Graduate School of Systemic Neurosciences, LMU, Munich, Germany. [2] Institute of Stem Cell Research, Helmholtz Zentrum Munich, Munich, Germany. [3] Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-Universität (JGU), Mainz, Germany. [4] Comprehensive Pneumology Center (CPC), Institute of Lung Health and Immunity (LHI), Helmholtz Zentrum Munich, Munich, Germany. [5] Member of the German Center for Lung Research (DZL), Airway Research Center North (ARCN), Grosshansdorf, Germany. [6] University Hospital, LMU, Munich, Germany. [7] German Center for Neurodegenerative Diseases (DZNE), Munich, Germany. [8] Imaging Core Facility, Biocenter, University of Würzburg, Würzburg, Germany. [9] Institute of Pathology, Faculty of Medicine, TUM, Munich, Germany. [10] Biomedical Center Munich (BMC), Institute of Physiological Genomics, LMU, Munich, Germany. [11] Institute of Clinical Neuroimmunology, Klinikum der Universität München, LMU, Munich, Germany. [12] Munich Cluster for Systems Neurology SyNergy, LMU, Munich, Germany. [13] Institute of Computational Biology, Helmholtz Zentrum Munich, Munich, Germany. [14] Research Center Borstel/Leibniz Lung Center, Borstel, Germany. [15] Institute of Experimental Medicine, Christian-Albrechts University Kiel, Kiel, Germany. [16] Institute of Molecular Biology (IMB), Mainz, Germany. [17] Biomedical Center Munich (BMC), Department of Cell Biology and Anatomy, Medical Faculty, LMU, Munich, Germany. ninkovic@helmholtz-muenchen.de. [18] Institute of Stem Cell Research, Helmholtz Zentrum Munich, Munich, Germany. ninkovic@helmholtz-muenchen.de. [19] Munich Cluster for Systems Neurology SyNergy, LMU, Munich, Germany. ninkovic@helmholtz-muenchen.de. [20]
DOI 10.1038/s41593-022-01199-y
PMID 36424432
发布时间 2023-03-02
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