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RIG-I and TLR-7/8 agonists as combination adjuvant shapes unique antibody and cellular vaccine responses to seasonal influenza vaccine.

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第一作者： Sonia,Jangra

第一单位： Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

作者： Sonia,Jangra ^[1] ; Gabriel,Laghlali ^[1] ; Angela,Choi ^[2] ; Raveen,Rathnasinghe ^[2] ; Yong,Chen ^[3] ; Soner,Yildiz ^[1] ; Lynda,Coughlan ^[4] ; Adolfo,García-Sastre ^[5] ; Bruno G,De Geest ^[3] ; Michael,Schotsaert ^[1]

作者单位： Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States. ^[1] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, United States. ^[2] Department of Pharmaceutics, Ghent University, Ghent, Belgium. ^[3] Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.;University of Maryland School of Medicine, Centre for Vaccine Development and Global Health (CVD), Baltimore, MD, United States. ^[4] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, United States.;The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States. ^[5]

关键词 ADCC HA stalk T cell adjuvant antibody class switching influenza vaccine neuraminidase