首页> The oncologist> Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study).

Morphine Versus Oxycodone for Cancer Pain Using a Catechol-O-methyltransferase Genotype Biomarker: A Multicenter, Randomized, Open-Label, Phase III Clinical Trial (RELIEF Study).

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第一作者： Hiromichi,Matsuoka

第一单位： Department of Psychosomatic Medicine, Kindai University Faculty of Medicine, Osaka, Japan.;Palliative Care Center, Kindai Hospital, Osaka, Japan.;Palliative Care Team, National Cancer Center, Tokyo, Japan.

作者： Hiromichi,Matsuoka ^[1] ; Junji,Tsurutani ^[2] ; Yasutaka,Chiba ^[3] ; Yoshihiko,Fujita ^[4] ; Kiyohiro,Sakai ^[5] ; Takeshi,Yoshida ^[6] ; Miki,Nakura ^[7] ; Ryo,Sakamoto ^[7] ; Chihiro,Makimura ^[7] ; Yoichi,Ohtake ^[8] ; Kaoru,Tanaka ^[9] ; Hidetoshi,Hayashi ^[9] ; Masayuki,Takeda ^[9] ; Tatsuya,Okuno ^[9] ; Naoki,Takegawa ^[9] ; Koji,Haratani ^[9] ; Atsuko,Koyama ^[5] ; Kazuto,Nishio ^[4] ; Kazuhiko,Nakagawa ^[9]

作者单位： Department of Psychosomatic Medicine, Kindai University Faculty of Medicine, Osaka, Japan.;Palliative Care Center, Kindai Hospital, Osaka, Japan.;Palliative Care Team, National Cancer Center, Tokyo, Japan. ^[1] Advanced Cancer Translational Research Institute, Showa University, Tokyo, Japan.;Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka, Japan. ^[2] Department of Biostatics, Kindai University Faculty of Medicine, Osaka, Japan. ^[3] Department of Genome Biology, Kindai University Faculty of Medicine, Osaka, Japan. ^[4] Department of Psychosomatic Medicine, Kindai University Faculty of Medicine, Osaka, Japan.;Palliative Care Center, Kindai Hospital, Osaka, Japan. ^[5] Palliative Care Center, Kindai Hospital, Osaka, Japan.;Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka, Japan. ^[6] Department of Psychosomatic Medicine, Kindai University Faculty of Medicine, Osaka, Japan. ^[7] Department of Psychosomatic Medicine, Kindai University Faculty of Medicine, Osaka, Japan.;Department of Internal Medicine, Sakai City Medical Center, Osaka, Japan. ^[8] Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka, Japan. ^[9]

关键词 biomarker cancer pain genotype humans morphine opioid analgesics