Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson's Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways.

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作者： Inayat Ur,Rehman ^[1] ; Amjad,Khan ^[1] ; Riaz,Ahmad ^[1] ; Kyonghwan,Choe ^[1] ; Hyun Young,Park ^[2] ; Hyeon Jin,Lee ^[2] ; Abubakar,Atiq ^[3] ; Jungsung,Park ^[1] ; Jong Ryeal,Hahm ^[1] ; Myeong Ok,Kim ^[1]

作者单位： Division of Life Sciences and Applied Life Science (BK 21 Four), College of Natural Science, Gyeongsang National University, Jinju 52828, Republic of Korea. ^[1] Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 ER Maastricht, The Netherlands. ^[2] Department of Pediatrics, Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands. ^[3] Division of Endocrinology and Metabolism, Department of Internal Medicine, Gyeongsang National University Hospital and Institute of Health Sciences and Department of Internal Medicine, College of Medicine, Gyeongsang National University, Jinju 52828, Republic of Korea. ^[4] Alz-Dementia Korea Co., Jinju 52828, Republic of Korea. ^[5]

关键词 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)intraperitoneal (i.p)nicotinamide (NAM)substantia nigra pars compacta (SNpc)

DOI 10.3390/biomedicines10112929

PMID 36428497

发布时间 2022-12-13

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Biomedicines

2022年10卷11期

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Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson's Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways.

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Neuroprotective Effects of Nicotinamide against MPTP-Induced Parkinson's Disease in Mice: Impact on Oxidative Stress, Neuroinflammation, Nrf2/HO-1 and TLR4 Signaling Pathways.

Biomedicines

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Biomedicines

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