SNPs in 3'UTR miRNA Target Sequences Associated with Individual Drug Susceptibility.

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作者： Elena,Rykova ^[1] ; Nikita,Ershov ^[2] ; Igor,Damarov ^[3] ; Tatiana,Merkulova ^[1]

作者单位： Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia. ^[1] Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Sciences, 630090 Novosibirsk, Russia. ^[2] Department of Engineering Problems of Ecology, Novosibirsk State Technical University, 630087 Novosibirsk, Russia. ^[3]

关键词 3′untranslated regions (3′UTRs)PASSPORT-seq VEGFR1 allele-specific expression (ASE)drug response luciferase reporter assay miRNA target sites microRNA (miRNA)pharmacogenes single nucleotide polymorphisms (SNPs)

主题词人类(Humans);3'非翻译区(3' Untranslated Regions);多态性, 单核苷酸(Polymorphism, Single Nucleotide);微RNAs(MicroRNAs);RNA, 信使(RNA, Messenger);结合部位(Binding Sites)

DOI 10.3390/ijms232213725

PMID 36430200

发布时间 2022-12-13

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