Synthesis, Cytotoxicity and Antiviral Activity Against Vaccinia Virus of 2-(3-Coumarinyl)-1-Hydroxyimidazoles.

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作者： Polina A,Nikitina ^[1] ; Anastasia M,Zakharova ^[2] ; Olga A,Serova ^[1] ; Nikolay I,Bormotov ^[3] ; Oleg Y,Mazurkov ^[3] ; Larisa N,Shishkina ^[3] ; Tatiana Y,Koldaeva ^[3] ; Elizaveta I,Basanova ^[1] ; Valery P,Perevalov ^[1]

作者单位： Department of Fine Organic Synthesis and Chemistry of Dyes, D.I. Mendeleev University of Chemical Technology of Russia, Miusskaya sq., 9, Moscow, 125047, Russia. ^[1] A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilova str., 28, Moscow, 119991, Russia. ^[2] State Research Center of Virology and Biotechnology "VECTOR," Novosibirsk Region, Koltsovo, 6300559, Russia. ^[3]

关键词 1-hydroxyimidazole Vaccinia virus antiviral activity chromone coumarin cytotoxicity orthopoxvirus prototropic tautomerism

主题词动物(Animals);人类(Humans);痘苗病毒(Vaccinia virus);抗病毒药(Antiviral Agents);天花(Smallpox);正痘病毒属(Orthopoxvirus);Vero细胞(Vero Cells)

DOI 10.2174/1573406419666221125101053

PMID 36437720

发布时间 2023-05-16

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