Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture.

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第一作者： Hualin,Fu

第一单位： Institute of Nano Biomedicine and Engineering, School of Sensing Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, China.

作者： Hualin,Fu ^[1] ; Jilong,Li ^[2] ; Peng,Du ^[1] ; Weilin,Jin ^[3] ; Guo,Gao ^[1] ; Daxiang,Cui ^[2]

作者单位： Institute of Nano Biomedicine and Engineering, School of Sensing Science and Engineering, School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, China. ^[1] National Center for Translational Medicine, Shanghai Jiao Tong University, China. ^[2] Department of Colorectal Surgery, School of Medicine, Xinhua Hospital, Shanghai Jiao Tong University, China. ^[3]

关键词 Alzheimer's disease Aβ Cathepsin D intravascular haemolysis microaneurysm senile plaque

主题词人类(Humans);阿尔茨海默病(Alzheimer Disease);斑块, 淀粉样(Plaque, Amyloid);组织蛋白酶D(Cathepsin D);溶血(Hemolysis);淀粉样β肽类(Amyloid beta-Peptides);脑(Brain)

DOI 10.1002/1873-3468.14549

PMID 36448495

发布时间 2023-04-14

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