首页> Molecular informatics> Artificial neural network models driven novel virtual screening workflow for the identification and biological evaluation of BACE1 inhibitors.

Artificial neural network models driven novel virtual screening workflow for the identification and biological evaluation of BACE1 inhibitors.

导出 LinkOut

翻译打印收藏纠错

第一作者： Kushagra,Kashyap

第一单位： Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.;Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.

作者： Kushagra,Kashyap ^[1] ; Lalita,Panigrahi ^[2] ; Shakil,Ahmed ^[2] ; Mohammad Imran,Siddiqi ^[1]

作者单位： Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.;Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. ^[1] Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India. ^[2]

关键词 alzheimer's disease artificial neural network beta-site amyloid-β precursor protein-cleaving enzyme 1 central nervous system multiparameter optimization molecular docking virtual screening

主题词淀粉样前体蛋白分泌酶类(Amyloid Precursor Protein Secretases);天冬氨酸内肽酶类(Aspartic Acid Endopeptidases);淀粉样β肽类(Amyloid beta-Peptides);工作流(Workflow);淀粉样β蛋白前体(Amyloid beta-Protein Precursor)

DOI 10.1002/minf.202200113

PMID 36460626

发布时间 2023-04-13

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交